^
Association details:
Biomarker:RUNX1 overexpression
Cancer:Glioma
Drug:temozolomide (DNA synthesis inhibitor)
Direction:Resistant
Evidence:
Evidence Level:
Resistant: D – Preclinical
Title:

Circ-VPS18 Knockdown Enhances TMZ Sensitivity and Inhibits Glioma Progression by MiR-370/RUNX1 Axis

Published date:
11/13/2020
Excerpt:
Circ-VPS18 expression and the mRNA and protein levels of RUNX1 were dramatically upregulated, and miR-370 expression was significantly downregulated in glioma cells, TMZ-resistant glioma tissues, or tissue compared with control groups.
DOI:
10.1007/s12031-020-01749-8