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Association details:
Biomarker:RPS26 expression
Cancer:Cervical Cancer
Drug Class:PD1 inhibitor
Direction:Sensitive
Evidence:
Evidence Level:
Sensitive: C3 – Early Trials
Source:
Title:

Ribosomal protein S26 (RPS26) expression of advanced cervical cancer (CC) to predict response to programmed death-1 inhibitor combination therapy: A secondary analysis of the CIBI308ALTER-C201 trial.

Published date:
05/25/2023
Excerpt:
The PFS of patients from CIBI308ALTER-C201 trail was significantly longer among patients with RPS26 expression for 2+/3+ than 0/1+ (not reached v 9.877 months, p= 0.0497)….Our study suggested that RPS26 could be novel predictive biomarkers in patients with CC treated with PD-1 inhibitor combination therapy...
DOI:
10.1200/JCO.2023.41.16_suppl.e17520