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Association details:
| Biomarker: | ROR1 positive |
|---|---|
| Cancer: | Lung Cancer |
| Drug: | avipendekin pegol (NKTR-255) (IL-15R agonist) |
| Direction: | Sensitive |
Evidence:
Source:
Title:
1152 - NKTR-255, a polymer-conjugated IL-15, dramatically improves ROR1 CAR-T cell persistence and anti-tumor efficacy in an autochthonous model of ROR1+ lung cancer
Published date:
03/15/2023
Excerpt:
Together, our work shows that NKTR-255 dramatically improves the persistence, function, and anti-tumor activity of ROR1 CAR-T cells in an aggressive autochthonous model of ROR1+ lung cancer.
Secondary therapy:
T-lymphocyte cell therapy
