^
Association details:
| Biomarker: | ROR1 overexpression |
|---|---|
| Cancer: | Mantle Cell Lymphoma |
| Drug: | ONCT-808 (ROR1-targeted CAR-T immunotherapy) |
| Direction: | Sensitive |
Evidence:
Source:
Title:
230 ONCT-808 ROR1 CAR T cells induce significant cancer cell death in mantle cell lymphoma cell line-derived CDX models and in vitro killing assays
Published date:
11/04/2023
Excerpt:
ONCT-808 demonstrated high efficacy in inducing ROR1 specific cancer cell death in both in vivo and in vitro studies, suggesting its potential in treating human cancer patients...ONCT-808 demonstrated high efficacy in inducing ROR1 specific cancer cell death in both in vivo and in vitro studies, suggesting its potential in treating human cancer patients.
DOI:
10.1136/jitc-2023-SITC2023.0230
