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Association details:
| Biomarker: | RNF43 mutation |
|---|---|
| Cancer: | Bladder Cancer |
| Drug Class: | Immunotherapy |
| Direction: | Sensitive |
Evidence:
Source:
Title:
RNF43 mutations to predict survival from treatment with immune checkpoint inhibitors and are associated with a high tumor mutation burden in bladder cancer.
Published date:
05/19/2021
Excerpt:
...patients with RNF43 mutations had significantly longer OS (25 months vs 8 months; p = 0.015)...RNF43 mutations may be a predictor of survival benefit from ICIs in bladder cancer…
