^
Association details:
| Biomarker: | RET mutation |
|---|---|
| Cancer: | Thyroid Gland Carcinoma |
| Drug: | LDD-2633 (RET inhibitor) |
| Direction: | Sensitive |
Evidence:
Source:
Title:
Characterization of LDD-2633 as a Novel RET Kinase Inhibitor with Anti-Tumor Effects in Thyroid Cancer
Published date:
01/06/2021
Excerpt:
...the anti-tumor activity of a novel RET inhibitor was characterized in medullary thyroid carcinoma cells....The growth of TT thyroid carcinoma cells harboring an RET mutation was suppressed by LDD-2633 treatment via the proliferation suppression and the induction of apoptosis.
DOI:
10.3390/ph14010038
