Evidence Level:Sensitive: C3 – Early Trials
Title:
BOS172738, a highly potent and selective RET inhibitor, for the treatment of RET-altered tumors including RET-fusion+ NSCLC and RET-mutant MTC: Phase 1 study results.
Excerpt:…67 patients with RET-altered advanced solid tumors received once-daily oral doses of BOS172738 (10-150 mg)….one patient with RET fusion+ pancreatic cancer reported a partial response.
DOI:10.1200/JCO.2021.39.15_suppl.3008