^
Association details:
| Biomarker: | REST signature |
|---|---|
| Cancer: | Glioblastoma |
| Drug: | Votrient (pazopanib) (Multi-tyrosine kinase inhibitor) |
| Direction: | Sensitive |
Evidence:
Source:
Title:
An expression based REST signature predicts patient survival and therapeutic response for glioblastoma multiforme
Excerpt:
…we developed an expression based REST signature and assessed its association with transcriptomics, genomics, drug sensitivity and clinical outcome for GBM in this article...cell lines with high REST activity were also more sensitive to VEGFR inhibition targeted by Pazopanib (Fig. 4A).
DOI:
10.1038/srep34556
