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Association details:
| Biomarker: | REST signature |
|---|---|
| Cancer: | Glioblastoma |
| Drug: | mitomycin (DNA synthesis inhibitor) |
| Direction: | Sensitive |
Evidence:
Source:
Title:
An expression based REST signature predicts patient survival and therapeutic response for glioblastoma multiforme
Excerpt:
...we developed an expression based REST signature and assessed its association with transcriptomics, genomics, drug sensitivity and clinical outcome for GBM in this article….cell lines with low REST activity were more sensitive to cytotoxic drugs including Mitomycin, Camptothecin and Cisplatin (Fig. 4A).
DOI:
10.1038/srep34556
