^
Association details:
| Biomarker: | RB1 negative |
|---|---|
| Cancer: | Triple Negative Breast Cancer |
| Drug: | VRN08 (TTK inhibitor) |
| Direction: | Sensitive |
Evidence:
Source:
Title:
LB119 - VRN08, a Selective Mps1 Kinase Inhibitor Induces Mitotic Catastrophe and Apoptosis Efficiently in Advanced Cancers Including Rb1-Deficient
Published date:
04/09/2021
Excerpt:
...VRN081569 efficiently induce apoptosis of Rb1-negative Triple Negative Breast Cancer (TNBC) cell line MDA-MB-468 than Rb1-positive TNBC MDA-MB-231.
