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Association details:
Biomarker:RAS mutation
Cancer:Colorectal Cancer
Drug Class:EGFR inhibitor
Direction:Sensitive
Evidence:
Evidence Level:
Sensitive: C3 – Early Trials
New
Source:
Title:

Second line EGFR-inhibitors in RAS mutant metastatic colorectal cancer: The plasma RAS wild type “window of opportunity”

Published date:
10/09/2018
Excerpt:
15 mCRC patients harboring any RAS mutation in tumor tissue....5 of them have received EGFR inhibitors as a second-line treatment, achieving a durable clinical benefit.
DOI:
10.1093/annonc/mdy281.095