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Association details:
| Biomarker: | PTPRT overexpression |
|---|---|
| Cancer: | Breast Cancer |
| Drug: | Ixempra (ixabepilone) (Microtubule inhibitor) |
| Direction: | Resistant |
Evidence:
Source:
Title:
PTPRT Could Be a Treatment Predictive and Prognostic Biomarker for Breast Cancer
Published date:
08/10/2021
Excerpt:
Based on rocplot.plot, among those patients who received neoadjuvant taxane (AUC = 0.59, p = 3.1e − 7), anthracycline (AUC = 0.60, p = 1.1e − 11), ixabepilone (AUC = 0.61, p = 0.04), and FAC (AUC = 0.6, p = 6.6e − 3), the PTPRT expression level was higher in no-responders than those in responders....PTPRT could predict chemotherapy effectiveness and prognosis for breast cancer patients.
