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Association details:
| Biomarker: | PTK7 expression |
|---|---|
| Cancer: | Triple Negative Breast Cancer |
| Drug: | BCG033 (TROP-2-targeted antibody-drug conjugate, PTK7-targeted antibody-drug conjugate) |
| Direction: | Sensitive |
Evidence:
Source:
Title:
1163 A novel bispecific antibody-drug conjugate targeting PTK7 and TROP2, BCG033, demonstrates preclinical efficacy against triple-negative breast cancer xenografts
Published date:
11/04/2023
Excerpt:
BCG033 also demonstrated superior efficacy to PTK7 benchmark in patient-derived xenografts, including TNBC xenografts with varying PTK7 expression levels...
DOI:
http://dx.doi.org/10.1136/jitc-2023-SITC2023.1163
