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    Association details:
    Biomarker:PTEN expression
    Cancer:Squamous Cell Carcinoma of Head and Neck
    Drug:Erbitux (cetuximab) (EGFR inhibitor)
    Direction:Resistant
    Evidence:
    Evidence Level:
    Resistant: C3 – Early Trials
    Source:
    Cancer Biol Med
    Title:

    Biomarkers of cetuximab resistance in patients with head and neck squamous cell carcinoma

    Published date:
    04/17/2020
    Excerpt:
    ...loss of PTEN protein expression predicted resistance to cetuximab when combined to radiotherapy.
    DOI:
    10.20892/j.issn.2095-3941.2019.0153