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Association details:
Evidence:
Evidence Level:
Resistant: C4 – Case Studies
Title:

PTCH1-GLI1 Fusion-Positive Ovarian Tumor: Report of a Unique Case With Response to Tyrosine Kinase Inhibitor Pazopanib

Published date:
09/20/2021
Excerpt:
Herein, we report for the first time a PTCH1-GLI1 fusion in a primary ovarian tumor from a female patient aged 54 years who presented with a 21-cm right ovarian mass and mesenteric metastasis. The patient received 4 cycles of pembrolizumab and 2 cycles of trabectedin but developed multiple metastases.
Secondary therapy:
trabectedin
DOI:
10.6004/jnccn.2021.7058