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Association details:
| Biomarker: | PRDX1 overexpression |
|---|---|
| Cancer: | Cervical Cancer |
| Drug: | cisplatin (DNA synthesis inhibitor) |
| Direction: | Resistant |
Evidence:
Source:
Title:
Expression of thioredoxin 1 and peroxiredoxins in squamous cervical carcinoma and its predictive role in NACT
Excerpt:
...expression of thioredoxin 1, peroxiredoxin 1 and peroxiredoxin 2 protein was analyzed in 13 human cervical squamous cancer tissues...High expression levels of these proteins were related to a poor response to cisplatin-based neoadjuvant chemotherapy....
Secondary therapy:
Chemotherapy
DOI:
10.1186/s12885-019-6046-x
