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Association details:
| Biomarker: | PRDX1 exon 5-NTRK1 exon 12 fusion |
|---|---|
| Cancer: | Lung Adenocarcinoma |
| Drug Class: | Trk inhibitor |
| Direction: | Sensitive |
Evidence:
Source:
Title:
P37.01 - Detection of NTRK Rearrangements by Next-Generation Sequencing in Chinese Lung Carcinoma Patients
Published date:
01/12/2021
Excerpt:
A 63-year old Chinese male with PRDX1 exon5-NTRK1 exon12 fusion was diagnosed as advanced lung adenocarcinoma. After six-month treatment of TRK inhibitor, computed tomography (CT) scanning showed sustained partial response with reduction of lung lesions and disappearance of pleural effusion.
