EZH2-mediated PP2A inactivation confers resistance to HER2-targeted breast cancer therapy
Published date:
11/18/2020
Excerpt:
PPP2R2B expression showed marked downregulation in the relapsed metastatic tumors compared to the primary tumors (Pā=ā0.0035...), suggesting a correlation between PPP2R2B downregulation and trastuzumab resistance.