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Association details:
Biomarker:POLE A456P
Cancer:Colon Cancer
Drug Class:Immunotherapy
Direction:Sensitive
Evidence:
Evidence Level:
Sensitive: C3 – Early Trials
Source:
Title:

Clinicopathological and genomic characteristics of POLE-mutated colorectal cancer in a Chinese population

Published date:
05/19/2021
Excerpt:
A MSS patient with metastatic colon cancer harboring A456P POLE mutation responsed well to the immunotherpy and achieved a partial response.
DOI:
10.1200/JCO.2021.39.15_suppl.e15531