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Association details:
| Biomarker: | PlGF-L |
|---|---|
| Cancer: | Colorectal Cancer |
| Drug: | Avastin (bevacizumab) (VEGF-A inhibitor) |
| Direction: | Sensitive |
Evidence:
Source:
Title:
463P-Impact of plasma angiogenesis factors on the efficacy of 2nd-line chemotherapy combined with biologics in metastatic colorectal cancer (mCRC): Early efficacy results from GI-SCREEN CRC Ukit study
Published date:
09/13/2021
Excerpt:
In the BEV group, patients with low PlGF had significantly longer PFS (7.5 vs 4.2 m, HR 2.35, p<0.01)...The measurement of VEGF-A, VEGF-D and PlGF may contribute to predicting the efficacy of the 2L chemotherapy plus bevacizumab for mCRC.
