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Association details:
| Biomarker: | PLAC8 overexpression |
|---|---|
| Cancer: | Germ Cell Tumors |
| Drug: | etoposide oral (Topoisomerase II inhibitor, DNA inhibitor) |
| Direction: | Resistant |
Evidence:
Source:
Title:
2988 / 6 - PLAC8 confers the chemoresistance of placental site trophoblastic tumor and choriocarcinoma to etoposide in an autophagy-dependent manner
Published date:
06/22/2020
Excerpt:
PLAC8 over-expression conferred chemoresistance of trophoblast cells to etoposide...Therefore, PLAC8 may serve as a potential therapeutic target for the treatment of PSTT and choriocarcinoma.
