^
Association details:
| Biomarker: | PIK3CA mutation + IDH2 mutation + Chr del(1q) + Chr del(17) |
|---|---|
| Cancer: | Glioma |
| Drug: | temozolomide (DNA synthesis inhibitor) |
| Direction: | Sensitive |
Evidence:
Source:
Title:
Molecular subtype specific biomarkers improve prediction of temozolomide therapy in low grade glioma
Excerpt:
...PIK3CA, mutated in 20% IDHmut-codel patients, significantly correlated with PFS (p=0.03) and OS (p=0.02) in this cohort.
