^
Association details:
| Biomarker: | PIK3CA H1047R |
|---|---|
| Cancer: | Endometrial Cancer |
| Drug: | MEN1611 (PI3K inhibitor) |
| Direction: | Sensitive |
Evidence:
Source:
Title:
The Selective Class I PI3K Inhibitor CH5132799 Targets Human Cancers Harboring Oncogenic PIK3CA Mutations
Excerpt:
Potent antitumor activity against tumors with PIK3CA mutations was also evident in the ovarian cancer SK-OV-3 and endometrial cancer MFE-280 models (Fig. 3C).
DOI:
10.1158/1078-0432.CCR-10-2882
