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Association details:
Biomarker:PGP expression
Cancer:Sarcoma
Drug:gemcitabine (DNA synthesis inhibitor)
Direction:Sensitive
Evidence:
Evidence Level:
Sensitive: D – Preclinical
Title:

Analysis of Multiple Drug Resistance Mechanism in Different Types of Soft Tissue Sarcomas: Assessment of the Expression of ABC-Transporters, MVP, YB-1, and Analysis of Their Correlation with Chemosensitivity of Cancer Cells

Published date:
03/16/2022
Excerpt:
In synovial sarcomas 5 out of 6 samples were obtained from the relapsed patient, and in this subgroup, we showed strong positive correlation of Pgp expression with SI (Gem) (r = 0.97, p = 0.005).
DOI:
10.3390/ijms23063183