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Association details:
Biomarker:
PDZK1IP1 expression
Cancer:
Pancreatic Cancer
Drug:
gemcitabine
(
DNA synthesis inhibitor
)
Direction:
Sensitive
Evidence:
Evidence Level:
Sensitive: D – Preclinical
Source:
ESMO 2023
Title:
1655P - Nampt inhibitors re-sensitize MAP17 expressing pancreas tumors
Published date:
10/16/2023
Excerpt:
...MAP17-expressing PC cells showed better response to gemcitabine, 5-FU, cisplatin and osimertinib, as well as resistance to docetaxel, bortezomib and ixazomib.
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