^
Association details:
| Biomarker: | PDGFRB overexpression |
|---|---|
| Cancer: | Hepatocellular Cancer |
| Drug Class: | Tyrosine kinase inhibitor |
| Direction: | Sensitive |
Evidence:
Source:
Title:
Abstract LB-329: Pancancer proteomic investigation identifies overexpressed kinases as novel cancer dependent targets
Published date:
05/15/2020
Excerpt:
Finally, we demonstrated that a subset of HCC mouse models that overexpressed PDGFRB -as detected in parallel in human HCC cohorts- could be specifically treated by a receptor tyrosine kinase inhibitor.
DOI:
10.1158/1538-7445.AM2020-LB-329
