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Association details:
Biomarker:
PD-L1 overexpression
Cancer:
Oral Cancer
Drug:
Opdivo (nivolumab)
(
PD1 inhibitor
) +
sitravatinib (MGCD516)
(
Multi-tyrosine kinase inhibitor
)
Direction:
Sensitive
Evidence:
Evidence Level:
Sensitive: C3 – Early Trials
Source:
ASCO 2020
Title:
SNOW: Sitravatinib and nivolumab in oral cavity cancer (OCC) window of opportunity study
Published date:
05/13/2020
Excerpt:
Best responders (Pts S1-S2) had higher % of PD-L1+ TAMs at baseline.
DOI:
10.1200/JCO.2020.38.15_suppl.6569
Trial ID:
SNOW
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