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Association details:
Biomarker:PD-L1 expression
Cancer:Gastroesophageal Cancer
Drug Class:Immunotherapy
Direction:Sensitive
Evidence:
Evidence Level:
Sensitive: C3 – Early Trials
New
Title:

Clinical and Molecular Predictors of Response to Immune Checkpoint Inhibitors in Patients with Advanced Esophagogastric Cancer

Excerpt:
Patients with advanced EGC treated with ICIs…One-hundred sixty-one patients were treated with ICIs (110 with anti-PD-1/PD-L1 antibodies and 51 with anti-CTLA-4 and PD-1/PD-L1 antibodies)…. Patients treated with combination ICI and those with PD-L1-positive tumors had improved outcomes.
DOI:
10.1158/1078-0432.CCR-18-3603