Evidence Level:Sensitive: C3 – Early Trials
Title:
A multicenter, open-label, single-arm, phase II trial to evaluate the efficacy and safety of geptanolimab (GB226) in the treatment of patients (pts) with programmed cell death ligand 1 (PD-L1)–positive recurrent or metastatic cervical cancer, for whom prior platinum-containing chemotherapy has failed.
Excerpt:In part 2, PD-L1 positive (CPS≥1) pts with recurrent or metastatic cervical cancer who had received one or more lines of platinum-containing chemotherapy were enrolled and treated with GB226….GB226 demonstrated durable antitumor activity and manageable safety profile in pts with recurrent or metastatic cervical cancer.
DOI:10.1200/JCO.2023.41.16_suppl.5535