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Association details:
Biomarker:PD-L1 expression + MSI-H/dMMR
Cancer:Pancreatic Cancer
Drug Class:PD1 inhibitor
Direction:Sensitive
Evidence:
Evidence Level:
Sensitive: C4 – Case Studies
Title:

Safety and efficacy analysis of PD-1 inhibitors in combination with chemotherapy for advanced pancreatic cancer

Published date:
11/07/2022
Excerpt:
One patient achieved a complete response, nine patients had a partial response, five patients had stable disease and three patients had progressive disease. Progression-free survival and overall survival were shown to be significantly prolonged in both PD-L1-positive and high microsatellite instability (MSI-H) patients....Anti-PD-1 antibodies in combination with chemotherapy are safe and effective in the treatment of advanced pancreatic cancer.
Secondary therapy:
Chemotherapy
DOI:
10.2217/imt-2022-0196