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Association details:
Biomarker:PALB2 mutation
Cancer:Biliary Tract Cancer
Drug Class:PARP inhibitor
Direction:Sensitive
Evidence:
Evidence Level:
Sensitive: A2 - Guideline
New
Source:
Title:

Biliary tract cancer: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up☆

Excerpt:
Patients with BRCA1/2 or PALB2 mutations responding to platinum-based therapy can be considered for treatment with PARP inhibitors [V, B; ESCAT score: III-A].