^
Association details:
| Biomarker: | PAI1 expression |
|---|---|
| Cancer: | Rectal Cancer |
| Drug: | AZD1208 (PIM inhibitor) |
| Direction: | Sensitive |
Evidence:
Source:
Title:
PAI1 is a Marker of Bad Prognosis in Rectal Cancer but Predicts a Better Response to Treatment with PIM Inhibitor AZD1208
Published date:
04/30/2020
Excerpt:
In addition, we demonstrate that cells expressing PAI1 protein are more sensitive to the PIM inhibitor AZD1208, suggesting that PAI1 could be used to predict response to treatment with PIM inhibitors and to complement radiotherapy in rectal tumors.
DOI:
10.3390/cells9051071.
