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Association details:
Biomarker:NUP98-HOXD11 fusion + Chr t(2;11)(q31;p15)
Cancer:Acute Myelogenous Leukemia
Regimen: (etoposide IV + daunorubicin + cytarabine)
Direction:Sensitive
Evidence:
Evidence Level:
Sensitive: C4 – Case Studies
Title:

Successful treatment of acute myelomonocytic leukaemia with NUP98–HOXD11 fusion transcripts and monitoring of minimal residual disease

Published date:
01/24/2003
Excerpt:
A 15‐year‐old Japanese boy was referred...Although he achieved complete haematological remission after an 8‐d induction therapy, comprising cytosine arabinoside, daunorubicin and etoposide...an AML‐M4 patient with t(2;11 (q31;p15) and the NUP98–HOXD11 fusion transcripts....He is in continuous complete remission without any significant complications 24...months after his initial diagnosis.
DOI:
https://doi.org/10.1046/j.1365-2141.2003.04052