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Association details:
Biomarker:
NTRK2 fusion
Cancer:
Vulvar Cancer
Drug:
Rozlytrek (entrectinib)
(
ALK inhibitor
,
TrkB receptor inhibitor
,
TrkC kinase inhibitor
,
TrkA receptor inhibitor
,
ROS1 inhibitor
,
JAK2 inhibitor
,
TNK2 inhibitor
)
Direction:
Sensitive
Evidence:
Evidence Level:
Sensitive: A2 - Guideline
Source:
NCCN
Published date:
04/26/2021
Excerpt:
Vulvar cancer (Squamous cell carcinoma): Advanced or recurrent/metastatic disease…Biomarker-directed systemic therapy for second-line treatment…Larotectinib or entrectinib for NTRK gene fusion-positive tumors...
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