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Association details:
Evidence:
Evidence Level:
Sensitive: D – Preclinical
Title:

Patient-derived tumor organoids for personalized medicine in a patient with rare hepatocellular carcinoma with neuroendocrine differentiation: a case report

Published date:
07/01/2022
Excerpt:
...tumor organoids have been generated from the resected HCC-NED and extensively characterized….With genomic analysis revealing a NTRK1-mutation of unknown significance (kinase domain) and tumor organoids found to be sensitive to entrectinib, a pan-TRK inhibitor...
DOI:
https://doi.org/10.1038/s43856-022-00150-3