^
Association details:
Biomarker:NT5E underexpression
Cancer:Urothelial Cancer
Drug Class:PD-L1 inhibitor
Direction:Sensitive
Evidence:
Evidence Level:
Sensitive: C3 – Early Trials
Title:

Integrated multi-omics analysis identifies CD73 as a prognostic biomarker and immunotherapy response predictor in head and neck squamous cell carcinoma

Published date:
11/16/2022
Excerpt:
In addition, we used a cohort of metastatic urothelial carcinomas (IMvigor210 cohort) that had actually received anti-PD-L1 immunotherapy to validate this result, and CD73 expression was indeed lower in the group that responded to immunotherapy (P = 0.0025).
DOI:
10.3389/fimmu.2022.969034