^
Association details:
| Biomarker: | NT5E overexpression |
|---|---|
| Cancer: | Renal Cell Carcinoma |
| Drug: | sunitinib (c-KIT inhibitor, VEGFR inhibitor, PDGFR inhibitor) |
| Direction: | Resistant |
Evidence:
Source:
Title:
NT5E inhibition suppresses the growth of sunitinib-resistant cells and EMT course and AKT/GSK-3ß signaling pathway in renal cell cancer
Excerpt:
...explore...biomarkers for RCC treatment using human clear-cell renal cell carcinoma (ccRCC) cell line, 786-O. NT5E expression was upregulated in sunitinib-resistant RCC tissues and cells.
DOI:
10.1002/iub.1942
