^
Association details:
| Biomarker: | NSD1 mutation |
|---|---|
| Cancer: | Solid Tumor |
| Drug: | cisplatin (DNA synthesis inhibitor) |
| Direction: | Sensitive |
Evidence:
Source:
Title:
NSD1 mutations by HPV status in head and neck cancer: differences in survival and response to DNA-damaging agents
Excerpt:
...the pan-cancer cohort showed significantly increased sensitivity (p = 0.0198) to cisplatin for cell lines with NSD1 mutations (n = 18) compared to those with wild-type NSD1 (n = 798)...
DOI:
10.1186/s41199-019-0042-3
