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Association details:
Biomarker:
NRAS mutation
Cancer:
Melanoma
Drug:
SAB298
(
SRC-family kinase (SFK) inhibitor
)
Direction:
Sensitive
Evidence:
Evidence Level:
Sensitive: D – Preclinical
New
Source:
Oncotarget
Title:
A novel anti-melanoma SRC-family kinase inhibitor
Excerpt:
Three-way Kruskal-Wallis analysis of the dot-plot display Figure 2D) showed that the difference in the levels of response to SAB298 between the double-WT and NRAS-mutant melanoma cells were statistically significant, p-value = 0.002985.
DOI:
10.18632/oncotarget.26787
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