^
Association details:
Biomarker:NRAS mutation
Cancer:Melanoma
Drug:SAB298 (SRC-family kinase (SFK) inhibitor)
Direction:Sensitive
Evidence:
Evidence Level:
Sensitive: D – Preclinical
New
Source:
Title:

A novel anti-melanoma SRC-family kinase inhibitor

Excerpt:
Three-way Kruskal-Wallis analysis of the dot-plot display Figure 2D) showed that the difference in the levels of response to SAB298 between the double-WT and NRAS-mutant melanoma cells were statistically significant, p-value = 0.002985.
DOI:
10.18632/oncotarget.26787