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Association details:
Biomarker:
NRAS exon 3 mutation
Cancer:
Colorectal Cancer
Drug:
Erbitux (cetuximab)
(
EGFR inhibitor
)
Direction:
Resistant
Evidence:
Evidence Level:
Resistant: A2 - Guideline
New
Source:
NCCN
Excerpt:
Patients with any known KRAS mutation (exon 2, 3, 4) or NRAS mutation (exon 2, 3, 4) should not be treated with either cetuximab or panitumumab.
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