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    Association details:
    Biomarker:No biomarker
    Cancer:Squamous Cell Carcinoma of Head and Neck
    Drug:carboplatin (Tubulin polymerization promoter) +
    5-fluorouracil (Thymidylate synthase inhibitor)
    Direction:Sensitive
    Evidence:
    Evidence Level:
    Sensitive: A2 - Guideline
    New
    Source:
    ESMO.org
    Title:

    Pan-Asian adaptation of the EHNSeESMOeESTRO Clinical Practice Guidelines for the diagnosis, treatment and follow-up of patients with squamous cell carcinoma of the head and neck

    Excerpt:
    Recommendation 3: Treatment...In patients unfit for cisplatin, carboplatin combined with 5-FU or cetuximab concomitant to RT as well as hyperfractionated or accelerated RT without chemotherapy are treatment alternatives [II, A].
    DOI:
    https://doi.org/10.1016/j.esmoop.2021.100309