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Association details:
Biomarker:
No biomarker
Cancer:
Renal Cell Carcinoma
Drug:
sorafenib
(
Multi-tyrosine kinase inhibitor
,
pan-RAF inhibitor
)
Direction:
Sensitive
Evidence:
Evidence Level:
Sensitive: A1 - Approval
New
Source:
European Medicines Agency
Excerpt:
Nexavar is indicated for the treatment of patients with advanced renal cell carcinoma who have failed prior interferon-alpha or interleukin-2 based therapy or are considered unsuitable for such therapy.
Evidence Level:
Sensitive: A1 - Approval
New
Source:
FDA
Excerpt:
NEXAVAR is a kinase inhibitor indicated for the treatment of...Advanced renal cell carcinoma
Evidence Level:
Sensitive: A2 - Guideline
New
Source:
NCCN
Excerpt:
The NCCN Panel does not recommend sorafenib use for patients with stage IV non-clear cell RCC.
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