^
Association details:
| Biomarker: | No biomarker |
|---|---|
| Cancer: | Osteosarcoma |
| Drug: | carboplatin (Tubulin polymerization promoter) + cyclophosphamide (Alkylating agent) |
| Direction: | Sensitive |
Evidence:
Source:
Title:
Bone sarcomas: ESMO–PaedCan–EURACAN Clinical Practice Guidelines for diagnosis, treatment and follow-up
Excerpt:
Summary of recommendations...Treatment (locoregional and advanced disease)...Second-line ChT for recurrent OS includes ifosfamide or cyclophosphamide, possibly in association with etoposide and/or carboplatin [III, B], and other active drugs including gemcitabine and docetaxel [IV, C], sorafenib [III, B] or regorafenib [II, B].
DOI:
10.1093/annonc/mdy310
