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Association details:
Evidence:
Evidence Level:
Sensitive: A1 - Approval
New
Source:
Published date:
10/11/2019
Excerpt:
Docetaxel Injection is a microtubule inhibitor indicated for...Non-small Cell Lung Cancer (NSCLC): single agent for locally advanced or metastatic NSCLC after platinum therapy failure; and with cisplatin for unresectable, locally advanced or metastatic untreated NSCLC.
Evidence Level:
Sensitive: A1 - Approval
Excerpt:
Docetaxel Teva is indicated for the treatment of patients with locally advanced or metastatic non-small-cell lung cancer after failure of prior chemotherapy.
Evidence Level:
Sensitive: A2 - Guideline
Source:
Published date:
09/15/2020
Excerpt:
For patients with metastatic NSCLC who progress on combination therapy with PD-1/PD-L1 inhibitors/chemotherapy, subsequent therapy with docetaxel (with or without ramucirumab), pemetrexed (non squamous only), or gemcitabine is recommended...
Evidence Level:
Sensitive: B - Late Trials
Title:

Docetaxel maintenance therapy versus best supportive care after first-line chemotherapy with different dose docetaxel plus cisplatin for advanced non-small cell lung cancer (TFINE study, CTONG-0904): an open-label, randomized, phase III trial

Excerpt:
In this open-label, randomized, phase III study, newly diagnosed patients with advanced NSCLC were initially randomized (R1, 1:1) to receive first-line treatment with cisplatin 75 mg/m2 plus docetaxel 75 mg/m2 (DC75) or 60 mg/m2 (DC60) for up to 4 cycles....DCM significantly prolonged PFS compared to BSC (HR =0.57, median PFS =5.8 vs. 3.0 months, P=0.002)....Continuation maintenance treatment with docetaxel...improves PFS in patients with NSCLC.
DOI:
10.21037/atm-20-8078
Trial ID: