Neuroendocrine Tumors of the Gastrointestinal Tract (Well-Differentiated Grade 1/2): Locoregional Advanced Disease and/or Distant Metastases (if progression on octreotide or lanreotide)...Useful in Certain Circumstances...Cytotoxic chemotherapy, if no other options feasible (all category 3): Anticancer agents such as 5-fluorouracil (5-FU), capecitabine, dacarbazine, oxaliplatin, streptozocin, and temozolomide can be used in patients with progressive metastases for whom there are no other treatment options.