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    Association details:
    Biomarker:No biomarker
    Cancer:Mesothelioma
    Drug:cisplatin (DNA synthesis inhibitor) +
    Tomudex (raltitrexed) (Thymidylate synthase inhibitor)
    Direction:Sensitive
    Evidence:
    Evidence Level:
    Sensitive: A2 - Guideline
    New
    Source:
    ESMO.org
    Title:

    Malignant pleural mesothelioma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

    Excerpt:
    Recommendation 4...The first- and second-line treatment of unresectable mesothelioma...Anti-folate/platinum doublet is the only approved standard of care...Combination doublet chemotherapy of cisplatin, with either pemetrexed or raltitrexed, has shown a longer survival compared with cisplatin alone…
    DOI:
    doi:10.1093/annonc/mdv199