^
Association details:
Biomarker:No biomarker
Cancer:Mesothelioma
Drug:Avastin (bevacizumab) (VEGF-A inhibitor)
Direction:Sensitive
Evidence:
Evidence Level:
Sensitive: A2 - Guideline
New
Source:
Excerpt:
The NCCN Panel recommends (category 2A) adding bevacizumab to carboplatin/pemetrexed with or without maintenance bevacizumab as first-line therapy option for patients with unresectable MPM… Mesothelioma: Peritoneal….FIRST-LINE THERAPY...Cisplatin + pemetrexed + bevacizumab….Preferred (if nivolumab/ipilimumab first line)...Cisplatin + pemetrexed + bevacizumab
Secondary therapy:
cisplatin + pemetrexed; carboplatin + pemetrexed