TEMODAR is an alkylating drug indicated for the treatment of adult patients with...Newly diagnosed glioblastoma concomitantly with radiotherapy and then as maintenance treatment...Refractory anaplastic astrocytoma who have experienced disease progression on a drug regimen containing nitrosourea and procarbazine.

Temodal hard capsules is indicated for the treatment of...adult patients with newly diagnosed glioblastoma multiforme concomitantly with radiotherapy and subsequently as monotherapy treatment...children from the age of three years, adolescents and adult patients with malignant glioma, such as glioblastoma multiforme or anaplastic astrocytoma, showing recurrence or progression after standard therapy.

For glioblastoma, combined modality therapy with temozolomide (TMZ) and radiotherapy remains the standard of care.

...concurrent treatment with adjuvant temozolomide and alternating electric fields is a category 1 recommendation for newly diagnosed glioblastoma patients 70 years of age or younger who have a good PS. This is also considered a reasonable treatment option for patients older than 70 years of age with good PS and newly diagnosed glioblastoma... ADULT GLIOMA: GLIOBLASTOMA....Adjuvant Treatment, KPS ≥60...Preferred Regimens...RT + concurrent and adjuvant TMZ ± TTF ADULT GLIOMA: GLIOBLASTOMA....Recurrence Therapy....TMZ

For glioblastoma, combined modality therapy with temozolomide (TMZ) and radiotherapy remains the standard of care.