Venclyxto can be used with obinutuzumab in patients who have not previously been treated for CLL or with rituximab in patients who have received at least one previous treatment.

Acalabrutinib, ibrutinib, venetoclax + rituximab (VenR), duvelisib, and idelalisib + rituximab (IdR) are included as options for patients with relapsed or refractory disease, regardless of patient's age and comorbities...