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Association details:
Biomarker:
No biomarker
Cancer:
Chronic Lymphocytic Leukemia
Drug:
bendamustine
(
DNA replication inhibitor
)
Drug Class:
CD20 inhibitor
Direction:
Sensitive
Evidence:
Evidence Level:
Sensitive: A2 - Guideline
New
Source:
NCCN
Excerpt:
Chronic lymphocytic leukemia/Small lymphocytic lymphoma...CLL/SLL without del(17p)/TP53 mutation...First-line therapy…Other recommended regimens…Bendamustine (70 mg/m2 in cycle 1 with escalation to 90 mg/m2 if tolerated) + anti-CD20 monoclonal antibody (not recommended for frail patients).
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